研究業績(原著論文)
2021
Fis1 ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation.
Varuzhanyan G, Ladinsky MS, Yamashita SI, Abe M, Sakimura K, Kanki T, Chan DC*.
Development. 2021; 148(16): dev199686.
Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis.
Maruyama T, Alam JM, Fukuda T, Kageyama S, Kirisako H, Ishii Y, Shimada I, Ohsumi Y, Komatsu M, Kanki T, Nakatogawa H, Noda NN*.
Nat Struct Mol Biol. 2021; 28(7): 583-593.
オートファジーフォーラムでの解説記事
The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43.
Kakihana T, Takahashi M, Katsuragi Y, Yamashita SI, Sango J, Kanki T, Onodera O, Fujii M*.
iScience. 2021; 24(7): 102733.
Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse-induced muscle atrophy.
Yamashita SI#, Kyuuma M#, Inoue K#*, Hata Y, Kawada R, Yamabi M, Fujii Y, Sakagami J, Fukuda T, Furukawa K, Tsukamoto S, Kanki T*.
J Cell Physiol. 2021; 236(11): 7612-7624.
#Equal contribution
MITOL promotes cell survival by degrading Parkin during mitophagy.
Shiiba I, Takeda K, Nagashima S, Ito N, Tokuyama T, Yamashita SI, Kanki T, Komatsu T, Urano Y, Fujikawa Y, Inatome R, Yanagi S*.
EMBO Rep. 2021; 22(3): e49097.
Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase.
Fukuda T*, Sofyantoro F, Tai YT, Chia KH, Matsuda T, Murase T, Morozumi Y, Tatebe H, Kanki T, Shiozaki K*.
eLife. 2021; 10: e60969.