研究業績（原著論文）
FKBP8 LIRL‐dependent mitochondrial fragmentation facilitates mitophagy under stress conditions.
Yoo SM, Yamashita SI, Kim H, Na DH, Lee H, Kim SJ, Cho DH, Kanki T, Jung YK*.
FASEB J. 2020; 34(2): 2944-2957.
2019
Glaucoma-associated mutations in the optineurin gene have limited impact on Parkin-dependent mitophagy.
Chernyshova K#, Inoue K#, Yamashita SI*, Fukuchi T, Kanki T*.
Invest Ophthalmol Vis Sci. 2019; 60(10): 3625-3635.
#Equal contribution
2018
The PP2A-like protein phosphatase Ppg1 and the Far complex cooperatively counteract CK2-mediated phosphorylation of Atg32 to inhibit mitophagy.
Furukawa K*, Fukuda T, Yamashita SI, Saigusa T, Kurihara Y, Yoshida Y, Kirisako H, Nakatogawa H, Kanki T*.
Cell Rep. 2018; 23(12): 3579-3590.
オートファジーフォーラムでの解説記事
Cdc14 phosphatase promotes TORC1-regulated autophagy in yeast.
Kondo A, Mostofa MG, Miyake K, Terasawa M, Nafisa I, Yeasmin AMST, Waliullah TM, Kanki T, Ushimaru T*.
J Mol Biol. 2018; 430(11): 1671-1684.
H2AFX and MDC1 promote maintenance of genomic integrity in male germ cells.
Testa E, Nardozi D, Antinozzi C, Faieta M, Di Cecca S, Caggiano C, Fukuda T, Bonanno E, Zhenkun L, Maldonado A, Roig I, Di Giacomo M, Barchi M*.
J Cell Sci. 2018;131(6): jcs214411.
2017
Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases.
Chia KH#, Fukuda T#*, Sofyantoro F, Matsuda T, Amai T, Shiozaki K*.
eLife. 2017; 6: e30880.
#Equal contribution
2016
Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy.
Yamashita SI, Jin X, Furukawa K, Hamasaki M, Nezu A, Otera H, Saigusa T, Yoshimori T, Sakai Y, Mihara K, Kanki T*.
J Cell Biol. 2016; 215(5): 649-665.
オートファジーフォーラムでの解説記事
Constitutive activation of PINK1 protein leads to proteasome-mediated and non-apoptotic cell death independently of mitochondrial autophagy.
Akabane S, Matsuzaki K, Yamashita S, Arai K, Okatsu K, Kanki T, Matsuda N, Oka T*.
J Biol Chem. 2016; 291(31): 16162-16174.
2015
Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways.
Hirota Y, Yamashita S, Kurihara Y, Jin X, Aihara M, Saigusa T, Kang D, Kanki T*.
Autophagy. 2015; 11(2): 332-43.
オートファジーフォーラムでの解説記事
2014
Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast.
Aihara M, Jin X, Kurihara Y, Yoshida Y, Matsushima Y, Oku M, Hirota Y, Saigusa T, Aoki Y, Uchiumi T, Yamamoto T, Sakai Y, Kang D, Kanki T*.
J Cell Sci. 2014; 127(14): 3184-3196.
オートファジーフォーラムでの解説記事