研究業績（原著論文）
Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast.
Kurihara Y, Kanki T, Aoki Y, Hirota Y, Saigusa T, Uchiumi T, Kang D.
J Biol Chem. 2012; 287(5): 3265-3272.
2011
Phosphorylation of Serine 114 on Atg32 mediates mitophagy.
Aoki Y, Kanki T, Hirota Y, Kurihara Y, Saigusa T, Uchiumi T, Kang D.
Mol Biol Cell. 2011; 22(17): 3206-3217.
2009
A genomic screen for yeast mutants defective in selective mitochondria autophagy.
Kanki T, Wang K, Baba M, Bartholomew CR, Lynch-Day MA, Du Z, Geng J, Mao K, Yang Z, Yen WL, Klionsky DJ.
Mol Biol Cell. 2009; 20(22): 4730-4738.
Atg32 is a mitochondrial protein that confers selectivity during mitophagy.
Kanki T, Wang K, Cao Y, Baba M, Klionsky DJ.
Dev Cell. 2009; 17(1): 98-109.
2008
Mitophagy in yeast occurs through a selective mechanism.
Kanki T, Klionsky DJ.
J Biol Chem. 2008; 283(47): 32386-32393.
Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice.
Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H.
J Neurosci. 2008; 28(34): 8624-8634.
2007
The C-terminal tail of mitochondrial transcription factor a markedly strengthens its general binding to DNA.
Ohgaki K, Kanki T, Fukuoh A, Kurisaki H, Aoki Y, Ikeuchi M, Kim SH, Hamasaki N, Kang D.
J Biochem. 2007; 141(2): 201-211.
2006
Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations.
López LC, Schuelke M, Quinzii CM, Kanki T, Rodenburg RJ, Naini A, Dimauro S, Hirano M.
Am J Hum Genet. 2006; 79(6): 1125-1129.
2005
PDIP38 associates with proteins constituting the mitochondrial DNA nucleoid.
Cheng X, Kanki T, Fukuoh A, Ohgaki K, Takeya R, Aoki Y, Hamasaki N, Kang D.
J Biochem. 2005; 138(6): 673-678.
2004
Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA.
Kanki T, Ohgaki K, Gaspari M, Gustafsson CM, Fukuoh A, Sasaki N, Hamasaki N, Kang D.
Mol Cell Biol. 2004; 24(22): 9823-9834.